2WN9

Crystal structure of Aplysia ACHBP in complex with 4-0H-DMXBA

2WN9 の概要

• エントリーDOI: 10.2210/pdb2wn9/pdb
• 関連するPDBエントリー: 2BR7 2BR8 2BYN 2BYP 2BYQ 2BYR 2BYS 2C9T 2UZ6 2W8E 2W8F 2W8G
• 分子名称: SOLUBLE ACETYLCHOLINE RECEPTOR, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(E)-5,6-DIHYDRO-2,3'-BIPYRIDIN-3(4H)-YLIDENEMETHYL]-3-METHOXYPHENOL, ... (5 entities in total)
• 機能のキーワード: receptor, 4-0h-dmxba, acetylcholine binding protein
• 由来する生物種: APLYSIA CALIFORNICA (CALIFORNIA SEA HARE)
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 132442.93

構造登録者

Sulzenbacher, G.,Hibbs, R.,Shi, J.,Talley, T.,Conrod, S.,Kem, W.,Taylor, P.,Marchot, P.,Bourne, Y. (登録日: 2009-07-07, 公開日: 2009-09-01, 最終更新日: 2023-12-13)

• 主引用文献: Hibbs, R.E.,Sulzenbacher, G.,Shi, J.,Talley, T.T.,Conrod, S.,Kem, W.R.,Taylor, P.,Marchot, P.,Bourne, Y.; Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor.; Embo J., 28:3040-3051, 2009; PubMed: 19696737; DOI: 10.1038/emboj.2009.227

実験手法

X-RAY DIFFRACTION (1.75 Å)