2WKK

Identification of the glycan target of the nematotoxic fungal galectin CGL2 in Caenorhabditis elegans

2WKK の概要

• エントリーDOI: 10.2210/pdb2wkk/pdb
• 関連するPDBエントリー: 1UL9 1ULC 1ULD 1ULE 1ULF 1ULG
• 分子名称: GALECTIN-2, beta-D-galactopyranose-(1-4)-alpha-L-fucopyranose, beta-D-galactopyranose-(1-4)-alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: sugar-binding protein, lectin, galectin, secreted, cell wall, sugar binding, sugar binding protein, beta-galactoside binding lectin, fruiting body, extracellular matrix
• 由来する生物種: COPRINOPSIS CINEREA
• 細胞内の位置: Secreted, extracellular space, extracellular matrix : Q9P4R8
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 68895.77

構造登録者

Butschi, A.,Titz, A.,Waelti, M.,Olieric, V.,Paschinger, K.,Xiaoqiang, G.,Seeberger, P.H.,Wilson, I.B.H.,Aebi, M.,Hengartner, M.O.,Kuenzler, M. (登録日: 2009-06-14, 公開日: 2010-01-19, 最終更新日: 2023-12-13)

• 主引用文献: Butschi, A.,Titz, A.,Walti, M.A.,Olieric, V.,Paschinger, K.,Nobauer, K.,Guo, X.,Seeberger, P.H.,Wilson, I.B.H.,Aebi, M.,Hengartner, M.O.,Kunzler, M.; Caenorhabditis Elegans N-Glycan Core Beta-Galactoside Confers Sensitivity Towards Nematotoxic Fungal Galectin Cgl2.; Plos Pathog., 6:E717-, 2010; PubMed: 20062796; DOI: 10.1371/JOURNAL.PPAT.1000717

実験手法

X-RAY DIFFRACTION (1.5 Å)