2WK6
Structural features of native human thymidine phosphorylase and in complex with 5-iodouracil
Summary for 2WK6
Entry DOI | 10.2210/pdb2wk6/pdb |
Related | 1UOU 2J0F 2WK5 |
Descriptor | THYMIDINE PHOSPHORYLASE, 5-IODOURACIL (3 entities in total) |
Functional Keywords | glycosyltransferase, developmental protein, angiogenesis, 5-iodouracil, growth factor, enzyme kinetics, differentiation, disease mutation, thymidine phosphorylase, chemotaxis, transferase, mutagenesis, polymorphism |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 2 |
Total formula weight | 100484.57 |
Authors | Mitsiki, E.,Papageorgiou, A.C.,Iyer, S.,Thiyagarajan, N.,Prior, S.H.,Sleep, D.,Finnis, C.,Acharya, K.R. (deposition date: 2009-06-05, release date: 2009-07-07, Last modification date: 2023-12-13) |
Primary citation | Mitsiki, E.,Papageorgiou, A.C.,Iyer, S.,Thiyagarajan, N.,Prior, S.H.,Sleep, D.,Finnis, C.,Acharya, K.R. Structures of Native Human Thymidine Phosphorylase and in Complex with 5-Iodouracil. Biochem.Biophys.Res.Commun., 386:666-, 2009 Cited by PubMed: 19555658DOI: 10.1016/J.BBRC.2009.06.104 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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