2WK6

Structural features of native human thymidine phosphorylase and in complex with 5-iodouracil

2WK6 の概要

• エントリーDOI: 10.2210/pdb2wk6/pdb
• 関連するPDBエントリー: 1UOU 2J0F 2WK5
• 分子名称: THYMIDINE PHOSPHORYLASE, 5-IODOURACIL (3 entities in total)
• 機能のキーワード: glycosyltransferase, developmental protein, angiogenesis, 5-iodouracil, growth factor, enzyme kinetics, differentiation, disease mutation, thymidine phosphorylase, chemotaxis, transferase, mutagenesis, polymorphism
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 100484.57

構造登録者

Mitsiki, E.,Papageorgiou, A.C.,Iyer, S.,Thiyagarajan, N.,Prior, S.H.,Sleep, D.,Finnis, C.,Acharya, K.R. (登録日: 2009-06-05, 公開日: 2009-07-07, 最終更新日: 2023-12-13)

• 主引用文献: Mitsiki, E.,Papageorgiou, A.C.,Iyer, S.,Thiyagarajan, N.,Prior, S.H.,Sleep, D.,Finnis, C.,Acharya, K.R.; Structures of Native Human Thymidine Phosphorylase and in Complex with 5-Iodouracil.; Biochem.Biophys.Res.Commun., 386:666-, 2009; PubMed: 19555658; DOI: 10.1016/J.BBRC.2009.06.104

実験手法

X-RAY DIFFRACTION (2.5 Å)