2WCT

human SARS coronavirus unique domain (triclinic form)

2WCT の概要

• エントリーDOI: 10.2210/pdb2wct/pdb
• 関連するPDBエントリー: 2W2G
• 分子名称: NON-STRUCTURAL PROTEIN 3 (2 entities in total)
• 機能のキーワード: rna-binding protein, rna-binding, zinc-finger, thiol protease, hydrolase, rna binding protein
• 由来する生物種: SARS CORONAVIRUS
• 細胞内の位置: Non-structural protein 3: Host membrane ; Multi-pass membrane protein . Non-structural protein 4: Host membrane ; Multi-pass membrane protein . Non-structural protein 6: Host membrane ; Multi-pass membrane protein . Non-structural protein 7: Host cytoplasm, host perinuclear region . Non-structural protein 8: Host cytoplasm, host perinuclear region . Non-structural protein 9: Host cytoplasm, host perinuclear region . Non-structural protein 10: Host cytoplasm, host perinuclear region : P0C6U8
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 116923.27

構造登録者

Tan, J.,Vonrhein, C.,Smart, O.S.,Bricogne, G.,Bollati, M.,Hansen, G.,Mesters, J.R.,Hilgenfeld, R. (登録日: 2009-03-16, 公開日: 2009-05-26, 最終更新日: 2023-12-13)

• 主引用文献: Tan, J.,Vonrhein, C.,Smart, O.S.,Bricogne, G.,Bollati, M.,Kusov, Y.,Hansen, G.,Mesters, J.R.,Schmidt, C.L.,Hilgenfeld, R.; The Sars-Unique Domain (Sud) of Sars Coronavirus Contains Two Macrodomains that Bind G-Quadruplexes.; Plos Pathog., 5:428-, 2009; PubMed: 19436709; DOI: 10.1371/JOURNAL.PPAT.1000428

実験手法

X-RAY DIFFRACTION (2.79 Å)