2W93

Crystal structure of the Saccharomyces cerevisiae pyruvate decarboxylase variant E477Q in complex with the surrogate pyruvamide

2W93 の概要

• エントリーDOI: 10.2210/pdb2w93/pdb
• 関連するPDBエントリー: 1PVD 1PYD 1QPB 2VK1 2VK8
• 分子名称: PYRUVATE DECARBOXYLASE ISOZYME 1, THIAMINE DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: substrate activation, substrate regulation, lyase, nucleus, cytoplasm, magnesium, acetylation, phosphoprotein, allosteric enzyme, thiamine pyrophosphate, phenylalanine catabolism, tryptophan catabolism, pyruvate decarboxylase, branched-chain amino acid catabolism, metal-binding, thiohemiketal, decarboxylase
• 由来する生物種: SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 248931.42

構造登録者

Kutter, S.,Weiss, M.S.,Konig, S. (登録日: 2009-01-21, 公開日: 2009-02-03, 最終更新日: 2023-12-13)

• 主引用文献: Konig, S.,Spinka, M.,Kutter, S.; Allosteric Activation of Pyruvate Decarboxylases. A Never-Ending Story.; J.Mol.Catal., B Enzym., 61:100-, 2014; DOI: 10.1016/J.MOLCATB.2009.02.010

実験手法

X-RAY DIFFRACTION (1.6 Å)