Structural and biochemical analysis of human pathogenic astrovirus serine protease at 2.0 Angstrom resolution

Summary for 2W5E

DescriptorPUTATIVE SERINE PROTEASE, CADMIUM ION, CHLORIDE ION, ... (4 entities in total)
Functional Keywordscoiled coil, transmembrane, thiol protease, rna replication, ribosomal frameshifting, serine protease, catalytic triad, protease, membrane, hydrolase, antiviral, astrovirus
Biological sourceHUMAN ASTROVIRUS 1
Total number of polymer chains6
Total molecular weight109174.82
Speroni, S.,Rohayem, J.,Nenci, S.,Bonivento, D.,Robel, I.,Barthel, J.,Coutard, B.,Canard, B.,Mattevi, A. (deposition date: 2008-12-10, release date: 2009-03-10, Last modification date: 2011-07-13)
Primary citation
Speroni, S.,Rohayem, J.,Nenci, S.,Bonivento, D.,Robel, I.,Barthel, J.,Luzhkov, V.B.,Coutard, B.,Canard, B.,Mattevi, A.
Structural and Biochemical Analysis of Human Pathogenic Astrovirus Serine Protease at 2.0 A Resolution.
J.Mol.Biol., 387:1137-, 2009
PubMed: 19249313 (PDB entries with the same primary citation)
DOI: 10.1016/J.JMB.2009.02.044
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.254500.9%9.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report