2W5B
Human Nek2 kinase ATPgammaS-bound
Summary for 2W5B
Entry DOI | 10.2210/pdb2w5b/pdb |
Related | 2JAV 2W5A 2W5H |
Descriptor | SERINE/THREONINE-PROTEIN KINASE NEK2, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | transferase, meiosis, mitosis, cytoplasm, metal-binding, phosphoprotein, nucleotide-binding, magnesium, cell cycle, atp-binding, centrosome splitting, cell division |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Nucleus. Isoform 1: Nucleus, nucleolus. Isoform 2: Cytoplasm: P51955 |
Total number of polymer chains | 1 |
Total formula weight | 33215.46 |
Authors | Bayliss, R. (deposition date: 2008-12-08, release date: 2008-12-23, Last modification date: 2024-05-08) |
Primary citation | Westwood, I.,Cheary, D.M.,Baxter, J.E.,Richards, M.W.,Van Montfort, R.L.,Fry, A.M.,Bayliss, R. Insights Into the Conformational Variability and Regulation of Human Nek2 Kinase. J.Mol.Biol., 386:476-, 2009 Cited by PubMed: 19124027DOI: 10.1016/J.JMB.2008.12.033 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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