2W4R

Crystal structure of the regulatory domain of human LGP2

2W4R の概要

• エントリーDOI: 10.2210/pdb2w4r/pdb
• 分子名称: PROBABLE ATP-DEPENDENT RNA HELICASE DHX58, MERCURY (II) ION, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: innate immunity, immune response, nucleotide-binding, coiled coil, atp-binding, polymorphism, double-strand rna binding protein, helicase, hydrolase, cytoplasm, rna-binding
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Cytoplasm: Q96C10
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 66137.29

構造登録者

Pippig, D.A.,Hellmuth, J.C.,Cui, S.,Kirchhofer, A.,Lammens, K.,Lammens, A.,Schmidt, A.,Rothenfusser, S.,Hopfner, K.P. (登録日: 2008-12-01, 公開日: 2009-02-24, 最終更新日: 2023-12-13)

• 主引用文献: Pippig, D.A.,Hellmuth, J.C.,Cui, S.,Kirchhofer, A.,Lammens, K.,Lammens, A.,Schmidt, A.,Rothenfusser, S.,Hopfner, K.P.; The Regulatory Domain of the Rig-I Family ATPase Lgp2 Senses Double-Stranded RNA.; Nucleic Acids Res., 37:2014-, 2009; PubMed: 19208642; DOI: 10.1093/NAR/GKP059

実験手法

X-RAY DIFFRACTION (2.6 Å)