2W4L

Human dCMP deaminase

Summary for 2W4L

• Entry DOI: 10.2210/pdb2w4l/pdb
• Descriptor: DEOXYCYTIDYLATE DEAMINASE, ZINC ION, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: pyrimidine metabolism, nucleotide biosynthesis, zinc, hexamer, hydrolase, metal-binding, phosphoprotein, allosteric enzyme
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 6
• Total formula weight: 121447.17

Authors

Siponen, M.I.,Moche, M.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Dahlgren, L.G.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, A.,Johansson, I.,Karlberg, T.,Kotenyova, T.,Lehtio, L.,Nilsson, M.E.,Nyman, T.,Persson, C.,Sagemark, J.,Schuler, H.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Weigelt, J.,Welin, M.,Wikstrom, M.,Wisniewska, M.,Nordlund, P. (deposition date: 2008-11-28, release date: 2009-01-13, Last modification date: 2023-12-13)

• Primary citation: Siponen, M.I.,Moche, M.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Dahlgren, L.G.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, A.,Johansson, I.,Karlberg, T.,Kotenyova, T.,Lehtio, L.,Nilsson, M.E.,Nyman, T.,Persson, C.,Sagemark, J.,Schuler, H.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Weigelt, J.,Welin, M.,Wikstrom, M.,Wisniewska, M.,Nordlund, P.; The Crystal Structure of Human Dcmp Deaminase; To be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)