2W0H
X ray structure of Leishmania infantum Trypanothione reductase in complex with antimony and NADPH
Summary for 2W0H
Entry DOI | 10.2210/pdb2w0h/pdb |
Related | 2JK6 |
Descriptor | TRYPANOTHIONE REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, ANTIMONY (III) ION, ... (6 entities in total) |
Functional Keywords | fad, leishamnia, antimonials, flavoprotein, reduced nadph, oxidoreductase, redox-active center, trypanothione metabolism |
Biological source | LEISHMANIA INFANTUM |
Total number of polymer chains | 2 |
Total formula weight | 114012.68 |
Authors | Baiocco, P.,Colotti, G.,Franceschini, S.,Ilari, A. (deposition date: 2008-08-18, release date: 2009-04-28, Last modification date: 2023-12-13) |
Primary citation | Baiocco, P.,Colotti, G.,Franceschini, S.,Ilari, A. Molecular Basis of Antimony Treatment in Leishmaniasis. J.Med.Chem., 52:2603-, 2009 Cited by PubMed: 19317451DOI: 10.1021/JM900185Q PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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