2VXS
Structure of IL-17A in complex with a potent, fully human neutralising antibody
Summary for 2VXS
Entry DOI | 10.2210/pdb2vxs/pdb |
Descriptor | INTERLEUKIN-17A, FAB FRAGMENT, SULFATE ION, ... (5 entities in total) |
Functional Keywords | epitope, complex, antibody, secreted, cytokine, glycoprotein, interleukin-17 |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Secreted: Q16552 |
Total number of polymer chains | 12 |
Total formula weight | 251384.50 |
Authors | Gerhardt, S.,Hargreaves, D.,Pauptit, R.A.,Davies, R.A.,Russell, C.,Welsh, F.,Tuske, S.J.,Coales, S.J.,Hamuro, Y.,Needham, M.R.C.,Langham, C.,Barker, W.,Bell, P.,Aziz, A.,Smith, M.J.,Dawson, S.,Abbott, W.M. (deposition date: 2008-07-09, release date: 2009-07-14, Last modification date: 2023-12-13) |
Primary citation | Gerhardt, S.,Abbott, W.M.,Hargreaves, D.,Pauptit, R.A.,Davies, R.A.,Needham, M.R.,Langham, C.,Barker, W.,Aziz, A.,Snow, M.J.,Dawson, S.,Welsh, F.,Wilkinson, T.,Vaugan, T.,Beste, G.,Bishop, S.,Popovic, B.,Rees, G.,Sleeman, M.,Tuske, S.J.,Coales, S.J.,Hamuro, Y.,Russell, C. Structure of Il-17A in Complex with a Potent, Fully Human Neutralising Antibody. J.Mol.Biol., 394:905-, 2009 Cited by PubMed: 19835883DOI: 10.1016/J.JMB.2009.10.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.63 Å) |
Structure validation
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