2VXS

Structure of IL-17A in complex with a potent, fully human neutralising antibody

2VXS の概要

• エントリーDOI: 10.2210/pdb2vxs/pdb
• 分子名称: INTERLEUKIN-17A, FAB FRAGMENT, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: epitope, complex, antibody, secreted, cytokine, glycoprotein, interleukin-17
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• 細胞内の位置: Secreted: Q16552
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 251384.50

構造登録者

Gerhardt, S.,Hargreaves, D.,Pauptit, R.A.,Davies, R.A.,Russell, C.,Welsh, F.,Tuske, S.J.,Coales, S.J.,Hamuro, Y.,Needham, M.R.C.,Langham, C.,Barker, W.,Bell, P.,Aziz, A.,Smith, M.J.,Dawson, S.,Abbott, W.M. (登録日: 2008-07-09, 公開日: 2009-07-14, 最終更新日: 2023-12-13)

• 主引用文献: Gerhardt, S.,Abbott, W.M.,Hargreaves, D.,Pauptit, R.A.,Davies, R.A.,Needham, M.R.,Langham, C.,Barker, W.,Aziz, A.,Snow, M.J.,Dawson, S.,Welsh, F.,Wilkinson, T.,Vaugan, T.,Beste, G.,Bishop, S.,Popovic, B.,Rees, G.,Sleeman, M.,Tuske, S.J.,Coales, S.J.,Hamuro, Y.,Russell, C.; Structure of Il-17A in Complex with a Potent, Fully Human Neutralising Antibody.; J.Mol.Biol., 394:905-, 2009; PubMed: 19835883; DOI: 10.1016/J.JMB.2009.10.008

実験手法

X-RAY DIFFRACTION (2.63 Å)