2VXO

Human GMP synthetase in complex with XMP

Summary for 2VXO

• Entry DOI: 10.2210/pdb2vxo/pdb
• Related: 2VPI
• Descriptor: GMP SYNTHASE [GLUTAMINE-HYDROLYZING], XANTHOSINE-5'-MONOPHOSPHATE, SULFATE ION, ... (4 entities in total)
• Functional Keywords: proto-oncogene, phosphoprotein, guanine monophosphate synthetase, gmp biosynthesis, nucleotide-binding, purine biosynthesis, nucleotide metabolism, gmps, casp8, ligase, atp-binding
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 2
• Total formula weight: 156447.02

Authors

Welin, M.,Lehtio, L.,Andersson, J.,Arrowsmith, C.H.,Berglund, H.,Collins, R.,Dahlgren, L.G.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, A.,Johansson, I.,Karlberg, T.,Kotenyova, T.,Moche, M.,Nilsson, M.E.,Nyman, T.,Olesen, K.,Persson, C.,Sagemark, J.,Schueler, H.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Wisniewska, M.,Wikstrom, M.,Nordlund, P. (deposition date: 2008-07-08, release date: 2008-08-12, Last modification date: 2023-12-13)

• Primary citation: Welin, M.,Lehtio, L.,Johansson, A.,Flodin, S.,Nyman, T.,Tresaugues, L.,Hammarstrom, M.,Graslund, S.,Nordlund, P.; Substrate Specificity and Oligomerization of Human Gmp Synthetase; J.Mol.Biol., 425:4323-, 2013; PubMed: 23816837; DOI: 10.1016/J.JMB.2013.06.032

Experimental method

X-RAY DIFFRACTION (2.5 Å)