2VXL

Screening a Limited Structure-based Library Identifies UDP-GalNAc- Specific Mutants of alpha-1,3 Galactosyltransferase

2VXL の概要

• エントリーDOI: 10.2210/pdb2vxl/pdb
• 関連するPDBエントリー: 1FG5 1G8O 1G93 1GWV 1GWW 1GX0 1GX4 1K4V 1O7O 1O7Q 1VZT 1VZU 1VZX 2JCJ 2JCK 2JCL 2JCO 2VFZ 2VS3 2VS4 2VS5 2VXM
• 分子名称: N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: glycosyltransferase, galactosyltransferase, transmembrane, golgi apparatus, enzyme mechanism, glycoprotein, metal-binding, signal-anchor, alpha-1, membrane, manganese, transferase, transferase substrate specificity
• 由来する生物種: BOS TAURUS (BOVINE)
• 細胞内の位置: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: P14769
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 33019.60

構造登録者

Tumbale, P.,Jamaluddin, H.,Thiyagarajan, N.,Acharya, K.R.,Brew, K. (登録日: 2008-07-07, 公開日: 2008-09-23, 最終更新日: 2023-12-13)

• 主引用文献: Tumbale, P.,Jamaluddin, H.,Thiyagarajan, N.,Acharya, K.R.,Brew, K.; Screening a Limited Structure-Based Library Identifies Udp-Galnac-Specific Mutants of {Alpha}-1,3-Galactosyltransferase.; Glycobiology, 18:1036-, 2008; PubMed: 18782853; DOI: 10.1093/GLYCOB/CWN083

実験手法

X-RAY DIFFRACTION (2.7 Å)