2VVQ

Crystal structure of Mycobacterium tuberculosis ribose-5-phosphate isomerase B in complex with the inhibitor 5-deoxy-5-phospho-D- ribonate

Summary for 2VVQ

Entry DOI	10.2210/pdb2vvq/pdb
Related	1USL 2BES 2BET 2VVO 2VVP 2VVR
Descriptor	RIBOSE-5-PHOSPHATE ISOMERASE B, 5-O-phosphono-D-ribonic acid, SULFATE ION, ... (4 entities in total)
Functional Keywords	pentose phosphate pathway, rpib, rv2465c, isomerase, carbohydrate metabolism
Biological source	MYCOBACTERIUM TUBERCULOSIS
Total number of polymer chains	5
Total formula weight	87920.24
Authors	Kowalinski, E.,Roos, A.K.,Mariano, S.,Salmon, L.,Mowbray, S.L. (deposition date: 2008-06-10, release date: 2008-07-01, Last modification date: 2023-12-13)
Primary citation	Roos, A.K.,Mariano, S.,Kowalinski, E.,Salmon, L.,Mowbray, S.L. D-Ribose-5-Phosphate Isomerase B from Escherichia Coli is Also a Functional D-Allose-6-Phosphate Isomerase, While the Mycobacterium Tuberculosis Enzyme is not. J.Mol.Biol., 382:667-, 2008 Cited by PubMed: 18640127 DOI: 10.1016/J.JMB.2008.06.090 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation