2VVQ
Crystal structure of Mycobacterium tuberculosis ribose-5-phosphate isomerase B in complex with the inhibitor 5-deoxy-5-phospho-D- ribonate
Summary for 2VVQ
Entry DOI | 10.2210/pdb2vvq/pdb |
Related | 1USL 2BES 2BET 2VVO 2VVP 2VVR |
Descriptor | RIBOSE-5-PHOSPHATE ISOMERASE B, 5-O-phosphono-D-ribonic acid, SULFATE ION, ... (4 entities in total) |
Functional Keywords | pentose phosphate pathway, rpib, rv2465c, isomerase, carbohydrate metabolism |
Biological source | MYCOBACTERIUM TUBERCULOSIS |
Total number of polymer chains | 5 |
Total formula weight | 87920.24 |
Authors | Kowalinski, E.,Roos, A.K.,Mariano, S.,Salmon, L.,Mowbray, S.L. (deposition date: 2008-06-10, release date: 2008-07-01, Last modification date: 2023-12-13) |
Primary citation | Roos, A.K.,Mariano, S.,Kowalinski, E.,Salmon, L.,Mowbray, S.L. D-Ribose-5-Phosphate Isomerase B from Escherichia Coli is Also a Functional D-Allose-6-Phosphate Isomerase, While the Mycobacterium Tuberculosis Enzyme is not. J.Mol.Biol., 382:667-, 2008 Cited by PubMed: 18640127DOI: 10.1016/J.JMB.2008.06.090 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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