2VVP

Crystal structure of Mycobacterium tuberculosis ribose-5-phosphate isomerase B in complex with its substrates ribose 5-phosphate and ribulose 5-phosphate

2VVP の概要

• エントリーDOI: 10.2210/pdb2vvp/pdb
• 関連するPDBエントリー: 1USL 2BES 2BET 2VVO 2VVQ 2VVR
• 分子名称: RIBOSE-5-PHOSPHATE ISOMERASE B, 5-O-phosphono-D-ribose, RIBULOSE-5-PHOSPHATE, ... (4 entities in total)
• 機能のキーワード: rpib, rv2465c, isomerase, rare sugar, carbohydrate metabolism, pentose phosphate pathway
• 由来する生物種: MYCOBACTERIUM TUBERCULOSIS
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 88798.67

構造登録者

Kowalinski, E.,Roos, A.K.,Mariano, S.,Salmon, L.,Mowbray, S.L. (登録日: 2008-06-10, 公開日: 2008-07-01, 最終更新日: 2023-12-13)

• 主引用文献: Roos, A.K.,Mariano, S.,Kowalinski, E.,Salmon, L.,Mowbray, S.L.; D-Ribose-5-Phosphate Isomerase B from Escherichia Coli is Also a Functional D-Allose-6-Phosphate Isomerase, While the Mycobacterium Tuberculosis Enzyme is not.; J.Mol.Biol., 382:667-, 2008; PubMed: 18640127; DOI: 10.1016/J.JMB.2008.06.090

実験手法

X-RAY DIFFRACTION (1.65 Å)