2VUX
Human ribonucleotide reductase, subunit M2 B
Summary for 2VUX
Entry DOI | 10.2210/pdb2vux/pdb |
Descriptor | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2 B, FE (III) ION (2 entities in total) |
Functional Keywords | dna replication, de novo pathway, nucleotide metabolism, ribonucleotide reductase, rnr, iron, p53r2, casp8, nucleus, metal-binding, oxidoreductase, dna damage, dna repair, iron binding, subunit m2 b |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm: Q7LG56 |
Total number of polymer chains | 2 |
Total formula weight | 76040.45 |
Authors | Welin, M.,Moche, M.,Andersson, J.,Arrowsmith, C.H.,Berglund, H.,Busam, R.D.,Collins, R.,Dahlgren, L.G.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Herman, M.D.,Johansson, A.,Johansson, I.,Kallas, A.,Karlberg, T.,Kotenyova, T.,Lehtio, L.,Nilsson, M.E.,Nyman, T.,Persson, C.,Sagemark, J.,Schueler, H.,Svensson, L.,Thorsell, A.G.,Tresaugues, L.,van Den Berg, S.,Weigelt, J.,Wikstrom, M.,Nordlund, P.,Structural Genomics Consortium (SGC) (deposition date: 2008-05-31, release date: 2008-07-15, Last modification date: 2023-12-13) |
Primary citation | Welin, M.,Moche, M.,Arrowsmith, C.H.,Berglund, H.,Busam, R.D.,Collins, R.,Dahlgren, L.G.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Herman, M.D.,Johansson, A.,Johansson, I.,Kallas, A.,Karlberg, T.,Kotenyova, T.,Lehtio, L.,Nilsson, M.E.,Nyman, T.,Persson, C.,Sagemark, J.,Schueler, H.,Svensson, L.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Weigelt, J.,Wikstrom, M.,Nordlund, P. Human Ribonucleotide Reductase, Subunit M2 B To be Published, |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
Download full validation report