2VUA

Crystal Structure of the Botulinum Neurotoxin Serotype A binding domain

Summary for 2VUA

Entry DOI	10.2210/pdb2vua/pdb
Related	1UEE 2VU9 3BTA
Descriptor	BOTULINUM NEUROTOXIN A HEAVY CHAIN (2 entities in total)
Functional Keywords	ganglioside, receptor, toxin, membrane, secreted, metal-binding, hydrolase, metalloprotease, neurotoxin, protease
Biological source	CLOSTRIDIUM BOTULINUM
Total number of polymer chains	1
Total formula weight	51713.40
Authors	Stenmark, P.,Dupuy, J.,Stevens, R.C. (deposition date: 2008-05-22, release date: 2008-08-26, Last modification date: 2023-12-13)
Primary citation	Stenmark, P.,Dupuy, J.,Imamura, A.,Kiso, M.,Stevens, R.C. Crystal Structure of Botulinum Neurotoxin Type a in Complex with the Cell Surface Co-Receptor Gt1B- Insight Into the Toxin-Neuron Interaction. Plos Pathog., 4:E129-, 2008 Cited by PubMed: 18704164 DOI: 10.1371/JOURNAL.PPAT.1000129 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation