2VS5

THE BINDING OF UDP-GALACTOSE BY AN ACTIVE SITE MUTANT OF alpha-1,3 GALACTOSYLTRANSFERASE (alpha3GT)

2VS5 の概要

• エントリーDOI: 10.2210/pdb2vs5/pdb
• 関連するPDBエントリー: 1FG5 1G8O 1G93 1GWV 1GWW 1GX0 1GX4 1K4V 1O7O 1O7Q 1VZT 1VZU 1VZX 2JCJ 2JCK 2JCL 2JCO 2VFZ 2VS3 2VS4
• 分子名称: N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, MANGANESE (II) ION, GALACTOSE-URIDINE-5'-DIPHOSPHATE, ... (5 entities in total)
• 機能のキーワード: manganese, transferase, glycoprotein, metal-binding, active-site mutant, glycosyltransferase, n-acetyl lactosamine, signal-anchor, transmembrane, golgi apparatus, gt, udp, membrane, alpha3gt, galactose, alpha-3gt
• 由来する生物種: BOS TAURUS (BOVINE)
• 細胞内の位置: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: P14769
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 68939.29

構造登録者

Tumbale, P.,Jamaluddin, H.,Thiyagarajan, N.,Brew, K.,Acharya, K.R. (登録日: 2008-04-18, 公開日: 2008-07-15, 最終更新日: 2023-12-13)

• 主引用文献: Tumbale, P.,Jamaluddin, H.,Thiyagarajan, N.,Brew, K.,Acharya, K.R.; Structural Basis of Udp-Galactose Binding by Alpha- 1,3-Galactosyltransferase (Alpha3Gt): Role of Negative Charge on Aspartic Acid 316 in Structure and Activity.; Biochemistry, 47:8711-, 2008; PubMed: 18651752; DOI: 10.1021/BI800852A

実験手法

X-RAY DIFFRACTION (1.82 Å)