2VLW

Crystal structure of the muscarinic toxin MT7 diiodoTYR51 derivative.

Summary for 2VLW

Entry DOI	10.2210/pdb2vlw/pdb
Descriptor	MUSCARINIC M1-TOXIN1, ACETATE ION, SULFATE ION, ... (4 entities in total)
Functional Keywords	acetylcholine receptor inhibitor, green mamba snake toxin, hm1 muscarinic receptor, toxin, secreted, neurotoxin, diiodotyrosine, muscarinic toxin, postsynaptic neurotoxin
Biological source	DENDROASPIS ANGUSTICEPS (EASTERN GREEN MAMBA)
Cellular location	Secreted: Q8QGR0
Total number of polymer chains	2
Total formula weight	15733.86
Authors	Menez, R.,Granata, V.,Mourier, G.,Fruchart-Gaillard, C.,Menez, A.,Servant, D.,Stura, E.A. (deposition date: 2008-01-17, release date: 2008-10-14, Last modification date: 2023-12-13)
Primary citation	Fruchart-Gaillard, C.,Mourier, G.,Marquer, C.,Stura, E.,Birdsall, N.J.M.,Servent, D. Different Interactions between Mt7 Toxin and the Human Muscarinic M1 Receptor in its Free and N-Methylscopolamine-Occupied States. Mol.Pharmacol., 74:1554-, 2008 Cited by PubMed: 18784346 DOI: 10.1124/MOL.108.050773 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.39 Å)

Structure validation