2VLW

Crystal structure of the muscarinic toxin MT7 diiodoTYR51 derivative.

2VLW の概要

• エントリーDOI: 10.2210/pdb2vlw/pdb
• 分子名称: MUSCARINIC M1-TOXIN1, ACETATE ION, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: acetylcholine receptor inhibitor, green mamba snake toxin, hm1 muscarinic receptor, toxin, secreted, neurotoxin, diiodotyrosine, muscarinic toxin, postsynaptic neurotoxin
• 由来する生物種: DENDROASPIS ANGUSTICEPS (EASTERN GREEN MAMBA)
• 細胞内の位置: Secreted: Q8QGR0
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 15733.86

構造登録者

Menez, R.,Granata, V.,Mourier, G.,Fruchart-Gaillard, C.,Menez, A.,Servant, D.,Stura, E.A. (登録日: 2008-01-17, 公開日: 2008-10-14, 最終更新日: 2023-12-13)

• 主引用文献: Fruchart-Gaillard, C.,Mourier, G.,Marquer, C.,Stura, E.,Birdsall, N.J.M.,Servent, D.; Different Interactions between Mt7 Toxin and the Human Muscarinic M1 Receptor in its Free and N-Methylscopolamine-Occupied States.; Mol.Pharmacol., 74:1554-, 2008; PubMed: 18784346; DOI: 10.1124/MOL.108.050773

実験手法

X-RAY DIFFRACTION (1.39 Å)