2VLH

Quinonoid intermediate of Citrobacter freundii tyrosine phenol-lyase formed with methionine

Summary for 2VLH

Entry DOI	10.2210/pdb2vlh/pdb
Related	1TPL 2EZ1 2EZ2 2TPL 2VLF
Descriptor	TYROSINE PHENOL-LYASE, (2E)-2-{[(Z)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4(1H)-YLIDENE}METHYL]IMINO}-4-(METHYLSULFANYL)BUTANOIC ACID, POTASSIUM ION, ... (7 entities in total)
Functional Keywords	plp-dependent enzyme, quinonoid intermediate, lyase, pyridoxal phosphate, tyrosine degradation
Biological source	CITROBACTER FREUNDII
Total number of polymer chains	2
Total formula weight	104313.80
Authors	Milic, D.,Demidkina, T.V.,Matkovic-Calogovic, D.,Antson, A.A. (deposition date: 2008-01-14, release date: 2008-08-19, Last modification date: 2023-12-13)
Primary citation	Milic, D.,Demidkina, T.V.,Faleev, N.G.,Matkovic-Calogovic, D.,Antson, A.A. Insights Into the Catalytic Mechanism of Tyrosine Phenol-Lyase from X-Ray Structures of Quinonoid Intermediates. J.Biol.Chem., 283:29206-, 2008 Cited by PubMed: 18715865 DOI: 10.1074/JBC.M802061200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation