2VLH

Quinonoid intermediate of Citrobacter freundii tyrosine phenol-lyase formed with methionine

2VLH の概要

• エントリーDOI: 10.2210/pdb2vlh/pdb
• 関連するPDBエントリー: 1TPL 2EZ1 2EZ2 2TPL 2VLF
• 分子名称: TYROSINE PHENOL-LYASE, (2E)-2-{[(Z)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4(1H)-YLIDENE}METHYL]IMINO}-4-(METHYLSULFANYL)BUTANOIC ACID, POTASSIUM ION, ... (7 entities in total)
• 機能のキーワード: plp-dependent enzyme, quinonoid intermediate, lyase, pyridoxal phosphate, tyrosine degradation
• 由来する生物種: CITROBACTER FREUNDII
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 104313.80

構造登録者

Milic, D.,Demidkina, T.V.,Matkovic-Calogovic, D.,Antson, A.A. (登録日: 2008-01-14, 公開日: 2008-08-19, 最終更新日: 2023-12-13)

• 主引用文献: Milic, D.,Demidkina, T.V.,Faleev, N.G.,Matkovic-Calogovic, D.,Antson, A.A.; Insights Into the Catalytic Mechanism of Tyrosine Phenol-Lyase from X-Ray Structures of Quinonoid Intermediates.; J.Biol.Chem., 283:29206-, 2008; PubMed: 18715865; DOI: 10.1074/JBC.M802061200

実験手法

X-RAY DIFFRACTION (1.95 Å)