2VL3

Oxidized and reduced forms of human peroxiredoxin 5

2VL3 の概要

• エントリーDOI: 10.2210/pdb2vl3/pdb
• 関連するPDBエントリー: 1H4O 1HD2 1OC3 1URM 2VL2
• 分子名称: PEROXIREDOXIN-5 (2 entities in total)
• 機能のキーワード: thioredoxin peroxidase, alternative initiation, antioxidant enzyme, redox-active center, cytoplasm, peroxidase, peroxisome, antioxidant, polymorphism, mitochondrion, peroxiredoxin, oxidoreductase, transit peptide, thioredoxin fold
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 54581.55

構造登録者

Smeets, A.,Declercq, J.P. (登録日: 2008-01-08, 公開日: 2008-08-26, 最終更新日: 2023-12-13)

• 主引用文献: Smeets, A.,Marchand, C.,Linard, D.,Knoops, B.,Declercq, J.P.; The Crystal Structures of Oxidized Forms of Human Peroxiredoxin 5 with an Intramolecular Disulfide Bond Confirm the Proposed Enzymatic Mechanism for Atypical 2-Cys Peroxiredoxins.; Arch.Biochem.Biophys., 477:98-, 2008; PubMed: 18489898; DOI: 10.1016/J.ABB.2008.04.036

実験手法

X-RAY DIFFRACTION (1.83 Å)