2VK4

Crystal structure of pyruvate decarboxylase from Kluyveromyces lactis

Replaces:  2G1I

Summary for 2VK4

• Entry DOI: 10.2210/pdb2vk4/pdb
• Related: 2G1I
• Descriptor: PYRUVATE DECARBOXYLASE, THIAMINE DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: metal-binding, decarboxylase, dimer of dimers, substrate activation, thiamine diphosphate, tdp, tpp, lyase, magnesium, flavoprotein, thiamine pyrophosphate, asymmetric active sites
• Biological source: KLUYVEROMYCES LACTIS
• Total number of polymer chains: 4
• Total formula weight: 248665.52

Authors

Kutter, S.,Relle, S.,Wille, G.,Weiss, M.S.,Konig, S. (deposition date: 2007-12-17, release date: 2009-01-27, Last modification date: 2023-12-13)

• Primary citation: Konig, S.,Spinka, M.,Kutter, S.; Allosteric Activation of Pyruvate Decarboxylases. A Never-Ending Story.; J.Mol.Catal., B Enzym., 61:100-, 2014; DOI: 10.1016/J.MOLCATB.2009.02.010

Experimental method

X-RAY DIFFRACTION (1.95 Å)