2VJV

Crystal structure of the IS608 transposase in complex with left end 26-mer DNA hairpin and a 6-mer DNA representing the left end cleavage site

Summary for 2VJV

• Entry DOI: 10.2210/pdb2vjv/pdb
• Related: 2A6M 2A6O 2VHG 2VIC 2VIH 2VJU
• Descriptor: TRANSPOSASE ORFA, 5'-D(*DA*DA*DA*DG*DC*DC*DC*DC*DT*DA*DG*DC*DTP*DT *DT*DT*DA*DG*DC*DT*DA*DT*DG*DG*DG*DGP)-3', 5'-D(*DT*DA*DT*DT*DA*DCP)-3', ... (5 entities in total)
• Functional Keywords: dna-binding protein, protein-dna complex, huh motif, dna stem loop, transposition, dna binding protein
• Biological source: HELICOBACTER PYLORI; More
• Total number of polymer chains: 6
• Total formula weight: 56430.54

Authors

Barabas, O.,Ronning, D.R.,Guynet, C.,Hickman, A.B.,Ton-Hoang, B.,Chandler, M.,Dyda, F. (deposition date: 2007-12-13, release date: 2008-02-19, Last modification date: 2023-12-13)

• Primary citation: Barabas, O.,Ronning, D.R.,Guynet, C.,Hickman, A.B.,Ton-Hoang, B.,Chandler, M.,Dyda, F.; Mechanism of is200/is605 Family DNA Transposases: Activation and Transposon-Directed Target Site Selection.; Cell(Cambridge,Mass.), 132:208-, 2008; PubMed: 18243097; DOI: 10.1016/J.CELL.2007.12.029

Experimental method

X-RAY DIFFRACTION (1.9 Å)