2VJ8

Complex of human leukotriene A4 hydrolase with a hydroxamic acid inhibitor

2VJ8 の概要

• エントリーDOI: 10.2210/pdb2vj8/pdb
• 分子名称: LTA4H PROTEIN, ZINC ION, YTTERBIUM (III) ION, ... (7 entities in total)
• 機能のキーワード: hydroxamic acid, leukotriene hydrolase, zinc, protease, hydrolase, metalloprotease
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 70477.09

構造登録者

Thunnissen, M.M.G.M.,Andersson, B.,Wong, C.-H.,Samuelsson, B.,Haeggstrom, J.Z. (登録日: 2007-12-07, 公開日: 2008-01-15, 最終更新日: 2023-12-13)

• 主引用文献: Thunnissen, M.M.G.M.,Andersson, B.,Wong, C.-H.,Samuelsson, B.,Haeggstrom, J.Z.; Crystal Structures of Leukotriene A4 Hydrolase in Complex with Captopril and Two Competitive Tight-Binding Inhibitors; Faseb J., 16:1648-, 2002; PubMed: 12207002; DOI: 10.1096/FJ.01-1017FJE

実験手法

X-RAY DIFFRACTION (1.8 Å)