2VGK

Crystal structure of Actinomadura R39 DD-peptidase complexed with a peptidoglycan-mimetic cephalosporin

Summary for 2VGK

Entry DOI	10.2210/pdb2vgk/pdb
Related	1W79 1W8Q 1W8Y 2VGJ
Descriptor	D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, (2R)-2-AMINO-7-{[(1R)-1-CARBOXYETHYL]AMINO}-7-OXOHEPTANOIC ACID, SULFATE ION, ... (5 entities in total)
Functional Keywords	cell wall biogenesis/degradation, antibiotic resistance, peptidoglycan synthesis, protease, secreted, hydrolase, cell shape, carboxypeptidase, penicillin-binding, actinomadura, peptidoglycan, transpeptidase
Biological source	ACTINOMADURA SP.
Cellular location	Secreted: P39045
Total number of polymer chains	4
Total formula weight	203092.51
Authors	Sauvage, E.,kerff, F.,Herman, R.,Charlier, P. (deposition date: 2007-11-14, release date: 2008-11-25, Last modification date: 2023-12-13)
Primary citation	Sauvage, E.,Powell, A.J.,Heilemann, J.,Josephin, H.R.,Charlier, P.,Davies, C.,Pratt, R.F. Crystal Structures of Complexes of Bacterial Dd-Peptidases with Peptidoglycan-Mimetic Ligands: The Substrate Specificity Puzzle. J.Mol.Biol., 381:383-, 2008 Cited by PubMed: 18602645 DOI: 10.1016/J.JMB.2008.06.012 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation