2VGJ
Crystal structure of Actinomadura R39 DD-peptidase complexed with a peptidoglycan-mimetic cephalosporin
Summary for 2VGJ
Entry DOI | 10.2210/pdb2vgj/pdb |
Related | 1W79 1W8Q 1W8Y 2VGK |
Descriptor | D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, CEPHALOSPORIN, SULFATE ION, ... (5 entities in total) |
Functional Keywords | cell wall biogenesis/degradation, antibiotic resistance, peptidoglycan synthesis, protease, secreted, hydrolase, cell shape, carboxypeptidase, penicillin-binding, actinomadura, peptidoglycan, transpeptidase |
Biological source | ACTINOMADURA SP. |
Cellular location | Secreted: P39045 |
Total number of polymer chains | 4 |
Total formula weight | 203470.50 |
Authors | Sauvage, E.,kerff, F.,Herman, R.,Charlier, P. (deposition date: 2007-11-14, release date: 2008-11-25, Last modification date: 2023-12-13) |
Primary citation | Sauvage, E.,Powell, A.J.,Heilemann, J.,Josephin, H.R.,Charlier, P.,Davies, C.,Pratt, R.F. Crystal Structures of Complexes of Bacterial Dd-Peptidases with Peptidoglycan-Mimetic Ligands: The Substrate Specificity Puzzle. J.Mol.Biol., 381:383-, 2008 Cited by PubMed: 18602645DOI: 10.1016/J.JMB.2008.06.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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