2VCN

Structure of isoniazid (INH) bound to cytosolic soybean ascorbate peroxidase mutant W41A

Summary for 2VCN

Entry DOI	10.2210/pdb2vcn/pdb
Related	1OAF 1OAG 1V0H 2CL4 2GGN 2GHC 2GHD 2GHE 2GHH 2GHK 2VCF
Descriptor	ASCORBATE PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... (5 entities in total)
Functional Keywords	ascorbate peroxidase, inh, apx, isoniazid, peroxidase, oxidoreductase
Biological source	GLYCINE MAX (SOYBEAN)
Total number of polymer chains	1
Total formula weight	29460.76
Authors	Metcalfe, C.L.,Macdonald, I.K.,Brown, K.A.,Raven, E.L.,Moody, P.C.E. (deposition date: 2007-09-25, release date: 2007-12-04, Last modification date: 2023-12-13)
Primary citation	Metcalfe, C.L.,Macdonald, I.K.,Murphy, E.J.,Brown, K.A.,Raven, E.L.,Moody, P.C.E. The Tuberculosis Prodrug Isoniazid Bound to Activating Peroxidases. J.Biol.Chem., 283:6193-, 2008 Cited by PubMed: 18056997 DOI: 10.1074/JBC.M707412200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.2 Å)

Structure validation