2VAQ
STRUCTURE OF STRICTOSIDINE SYNTHASE IN COMPLEX WITH INHIBITOR
Summary for 2VAQ
Entry DOI | 10.2210/pdb2vaq/pdb |
Related | 2FP8 2FP9 2FPB 2FPC 2V91 |
Descriptor | STRICTOSIDINE SYNTHASE, (2S,3R,4S)-methyl 4-(2-(2-(1H-indol-3-yl)ethylamino)ethyl)-2-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-vinyl-3,4-dihydro-2H-pyran-5-carboxylate (3 entities in total) |
Functional Keywords | alkaloid metabolism, glycoprotein, lyase, six bladed beta propeller fold, str1, synthase, vacuole |
Biological source | RAUVOLFIA SERPENTINA (SERPENTWOOD) |
Total number of polymer chains | 2 |
Total formula weight | 72597.04 |
Authors | Maresh, J.,Giddings, L.A.,Friedrich, A.,Loris, E.A.,Panjikar, S.,Trout, B.L.,Stoeckigt, J.,Peters, B.,O'Connor, S.E. (deposition date: 2007-09-04, release date: 2008-09-16, Last modification date: 2023-12-13) |
Primary citation | Maresh, J.J.,Giddings, L.A.,Friedrich, A.,Loris, E.A.,Panjikar, S.,Trout, B.L.,Stockigt, J.,Peters, B.,O'Connor, S.E. Strictosidine synthase: mechanism of a Pictet-Spengler catalyzing enzyme. J. Am. Chem. Soc., 130:710-723, 2008 Cited by PubMed: 18081287DOI: 10.1021/ja077190z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.01 Å) |
Structure validation
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