2V9T

Complex between the second LRR domain of Slit2 and The first Ig domain from Robo1

Summary for 2V9T

• Entry DOI: 10.2210/pdb2v9t/pdb
• Related: 2V70 2V9Q 2V9R 2V9S
• Descriptor: ROUNDABOUT HOMOLOG 1, SLIT HOMOLOG 2 PROTEIN N-PRODUCT (3 entities in total)
• Functional Keywords: structural protein-receptor complex, developmental protein, ig domain, roundabout, chemotaxis, lrr domain, immunoglobulin domain, leucine-rich repeat, neuronal development, phosphorylation, egf-like domain, disease mutation, slit2, ligand, membrane, secreted, receptor, neurogenesis, glycoprotein, transmembrane, proto-oncogene, differentiation structural protein/receptor, complex, structural protein/receptor
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 2
• Total formula weight: 37780.24

Authors

Morlot, C.,Cusack, S.,McCarthy, A.A. (deposition date: 2007-08-25, release date: 2007-09-25, Last modification date: 2012-08-29)

• Primary citation: Morlot, C.,Thielens, N.M.,Ravelli, R.B.,Hemrika, W.,Romijn, R.A.,Gros, P.,Cusack, S.,Mccarthy, A.A.; Structural Insights Into the Slit-Robo Complex.; Proc.Natl.Acad.Sci.USA, 104:14923-, 2007; PubMed: 17848514; DOI: 10.1073/PNAS.0705310104

Experimental method

X-RAY DIFFRACTION (1.7 Å)