2V77

Crystal Structure of Human Carboxypeptidase A1

Summary for 2V77

Entry DOI	10.2210/pdb2v77/pdb
Descriptor	CARBOXYPEPTIDASE A1, OCTANE-1,3,5,7-TETRACARBOXYLIC ACID, ZINC ION, ... (5 entities in total)
Functional Keywords	metal-binding, metalloprotease, carboxypeptidase, protein degradation, zinc, zymogen, protease, secreted, hydrolase
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	2
Total formula weight	70835.95
Authors	Pallares, I.,Fernandez, D.,Comellas-Bigler, M.,Fernandez-Recio, J.,Ventura, S.,Aviles, F.X.,Vendrell, J. (deposition date: 2007-07-27, release date: 2008-07-01, Last modification date: 2023-12-13)
Primary citation	Pallares, I.,Fernandez, D.,Comellas-Bigler, M.,Fernandez-Recio, J.,Ventura, S.,Aviles, F.X.,Bode, W.,Vendrell, J. Direct interaction between a human digestive protease and the mucoadhesive poly(acrylic acid). Acta Crystallogr. D Biol. Crystallogr., D64:784-791, 2008 Cited by PubMed: 18566513 DOI: 10.1107/S0907444908013474 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.603 Å)

Structure validation