2V76
Crystal structure of the human dok1 PTB domain
Summary for 2V76
Entry DOI | 10.2210/pdb2v76/pdb |
Descriptor | DOCKING PROTEIN 1, TRIETHYLENE GLYCOL, SULFATE ION, ... (6 entities in total) |
Functional Keywords | protein-binding, ptb domain, phosphorylation, adaptor protein, protein binding |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Isoform 1: Cytoplasm. Isoform 3: Cytoplasm, perinuclear region: Q53TY2 |
Total number of polymer chains | 4 |
Total formula weight | 49197.60 |
Authors | Oxley, C.L.,Anthis, N.J.,Lowe, E.D.,Campbell, I.D.,Wegener, K.L. (deposition date: 2007-07-26, release date: 2008-01-08, Last modification date: 2023-12-13) |
Primary citation | Oxley, C.L.,Anthis, N.J.,Lowe, E.D.,Vakonakis, I.,Campbell, I.D.,Wegener, K.L. An Integrin Phosphorylation Switch: The Effect of {Beta}3 Integrin Tail Phosphorylation on Dok1 and Talin Binding. J.Biol.Chem., 283:5420-, 2008 Cited by PubMed: 18156175DOI: 10.1074/JBC.M709435200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
Download full validation report