2V6Q
Crystal Structure of a BHRF-1 : Bim BH3 complex
Summary for 2V6Q
Entry DOI | 10.2210/pdb2v6q/pdb |
Related | 2VM6 2WH6 |
Descriptor | BHRF1 PROTEIN, BCL-2-LIKE PROTEIN 11, BROMIDE ION, ... (4 entities in total) |
Functional Keywords | alternative splicing, bcl-2, membrane, apoptosis |
Biological source | HUMAN HERPESVIRUS 4 (EPSTEIN-BARR VIRUS) More |
Cellular location | Host membrane; Single-pass membrane protein (Potential): P03182 Endomembrane system; Peripheral membrane protein (By similarity). Isoform BimEL: Mitochondrion. Isoform BimL: Mitochondrion. Isoform BimS: Mitochondrion. Isoform Bim-alpha1: Mitochondrion: O43521 |
Total number of polymer chains | 2 |
Total formula weight | 23522.58 |
Authors | Kvansakul, M.,Huang, D.C.S.,Colman, P.M. (deposition date: 2007-07-20, release date: 2008-08-19, Last modification date: 2024-05-08) |
Primary citation | Kvansakul, M.,Wei, A.H.,Fletcher, J.I.,Willis, S.N.,Chen, L.,Roberts, A.W.,Huang, D.C.,Colman, P.M. Structural Basis for Apoptosis Inhibition by Epstein-Barr Virus Bhrf1. Plos Pathog., 6:1236-, 2010 Cited by PubMed: 21203485DOI: 10.1371/JOURNAL.PPAT.1001236 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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