2V6N

Crystal structures of the SARS-coronavirus main proteinase inactivated by benzotriazole compounds

2V6N の概要

• エントリーDOI: 10.2210/pdb2v6n/pdb
• 分子名称: REPLICASE POLYPROTEIN 1AB, 4-(DIMETHYLAMINO)BENZOIC ACID, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (5 entities in total)
• 機能のキーワード: thiol protease, rna replication, main proteinase, ribosomal frameshift, sars, protease, hydrolase, polyprotein, viral protein
• 由来する生物種: HUMAN SARS CORONAVIRUS (SARS-COV)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34333.13

構造登録者

Verschueren, K.H.G.,Pumpor, K.,Anemueller, S.,Mesters, J.R.,Hilgenfeld, R. (登録日: 2007-07-19, 公開日: 2008-07-01, 最終更新日: 2023-12-13)

• 主引用文献: Verschueren, K.H.G.,Pumpor, K.,Anemueller, S.,Chen, S.,Mesters, J.R.,Hilgenfeld, R.; A Structural View of the Inactivation of the Sars Coronavirus Main Proteinase by Benzotriazole Esters.; Chem.Biol., 15:597-, 2008; PubMed: 18559270; DOI: 10.1016/J.CHEMBIOL.2008.04.011

実験手法

X-RAY DIFFRACTION (1.98 Å)