2V5Y

Crystal structure of the receptor protein tyrosine phosphatase mu ectodomain

Summary for 2V5Y

Entry DOI	10.2210/pdb2v5y/pdb
Related	1RPM 2C9A
Descriptor	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE MU, 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION (3 entities in total)
Functional Keywords	membrane, receptor, hydrolase, glycoprotein, receptor protein tyrosine phosphatase, cell adhesion, transmembrane, protein phosphatase, extracellular region, immunoglobulin domain
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	83293.78
Authors	Aricescu, A.R.,Siebold, C.,Choudhuri, K.,Chang, V.T.,Lu, W.,Davis, S.J.,van der Merwe, P.A.,Jones, E.Y. (deposition date: 2007-07-11, release date: 2007-09-11, Last modification date: 2023-12-13)
Primary citation	Aricescu, A.R.,Siebold, C.,Choudhuri, K.,Chang, V.T.,Lu, W.,Davis, S.J.,Van Der Merwe, P.A.,Jones, E.Y. Structure of a Tyrosine Phosphatase Adhesive Interaction Reveals a Spacer-Clamp Mechanism. Science, 317:1217-, 2007 Cited by PubMed: 17761881 DOI: 10.1126/SCIENCE.1144646 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation