2V34

IspE in complex with cytidine and ligand

Summary for 2V34

• Entry DOI: 10.2210/pdb2v34/pdb
• Related: 2V2Q 2V2V 2V2Y 2V2Z
• Descriptor: 4-DIPHOSPHOCYTIDYL-2C-METHYL-D-ERYTHRITOL KINASE, 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: transferase, 4-diphosphocytidyl-2c-methyl-d-erythritol, aquifex aeolicus, nucleotide-binding, isoprene biosynthesis, kinase, atp-binding, non-mevalonate
• Biological source: AQUIFEX AEOLICUS
• Total number of polymer chains: 2
• Total formula weight: 61740.73

Authors

Sgraja, T.,Alphey, M.S.,Hunter, W.N. (deposition date: 2007-06-11, release date: 2007-06-26, Last modification date: 2024-05-08)

• Primary citation: Sgraja, T.,Alphey, M.S.,Ghilagaber, S.,Marquez, R.,Robertson, M.N.,Hemmings, J.L.,Lauw, S.,Rohdich, F.,Bacher, A.,Eisenreich, W.,Illarionova, V.,Hunter, W.N.; Characterization of Aquifex Aeolicus 4-Diphosphocytidyl-2C-Methyl-D-Erythritol Kinase -Ligand Recognition in a Template for Antimicrobial Drug Discovery.; FEBS J., 275:2779-, 2008; PubMed: 18422643; DOI: 10.1111/J.1742-4658.2008.06418.X

Experimental method

X-RAY DIFFRACTION (2.3 Å)