2V30

Human orotidine 5'-phosphate decarboxylase domain of uridine monophospate synthetase (UMPS) in complex with its product UMP.

2V30 の概要

• エントリーDOI: 10.2210/pdb2v30/pdb
• 関連するPDBエントリー: 2JGY
• 分子名称: OROTIDINE 5'-PHOSPHATE DECARBOXYLASE, URIDINE-5'-MONOPHOSPHATE (3 entities in total)
• 機能のキーワード: alternative splicing, pyrimidine metabolism, disease mutation, glycosyltransferase, ump, lyase, transferase, polymorphism, decarboxylase, multifunctional enzyme, pyrimidine biosynthesis
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 61910.83

構造登録者

Moche, M.,Ogg, D.,Arrowsmith, C.,Berglund, H.,Busam, R.,Collins, R.,Dahlgren, L.G.,Edwards, A.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg-Schiavone, L.,Johansson, I.,Kallas, A.,Karlberg, T.,Kotenyova, T.,Lehtio, L.,Nyman, T.,Persson, C.,Sagemark, J.,Stenmark, P.,Sundstrom, M.,Thorsell, A.G.,van den Berg, S.,Weigelt, J.,Welin, M.,Nordlund, P.,Structural Genomics Consortium (SGC) (登録日: 2007-06-10, 公開日: 2007-07-24, 最終更新日: 2023-12-13)

• 主引用文献: Moche, M.,Ogg, D.,Arrowsmith, C.,Berglund, H.,Busam, R.,Collins, R.,Dahlgren, L.G.,Edwards, A.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg-Schiavone, L.,Johansson, I.,Kallas, A.,Karlberg, T.,Kotenyova, T.,Lehtio, L.,Nyman, T.,Persson, C.,Sagemark, J.,Stenmark, P.,Sundstrom, M.,Thorsell, A.G.,van den Berg, S.,Weigelt, J.,Welin, M.,Nordlund, P.; The Crystal Structure of Human Orotidine 5'-Decarboxylase Domain of Human Uridine Monophosphate Synthetase (Umps); To be Published,

実験手法

X-RAY DIFFRACTION (2 Å)