2V2F
Crystal structure of PBP1a from drug-resistant strain 5204 from Streptococcus pneumoniae
Summary for 2V2F
Entry DOI | 10.2210/pdb2v2f/pdb |
Descriptor | PENICILLIN BINDING PROTEIN 1A, BARIUM ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (5 entities in total) |
Functional Keywords | transpeptidase activity, peptidoglycan synthesis, transferase, hydrolase |
Biological source | STREPTOCOCCUS PNEUMONIAE More |
Total number of polymer chains | 2 |
Total formula weight | 46404.52 |
Authors | Job, V.,Carapito, R.,Vernet, T.,Dideberg, O.,Dessen, A.,Zapun, A. (deposition date: 2007-06-05, release date: 2007-12-25, Last modification date: 2023-12-13) |
Primary citation | Job, V.,Carapito, R.,Vernet, T.,Dessen, A.,Zapun, A. Common Alterations in Pbp1A from Resistant Streptococcus Pneumoniae Decrease its Reactivity Toward {Beta}-Lactams: Structural Insights. J.Biol.Chem., 283:4886-, 2008 Cited by PubMed: 18055459DOI: 10.1074/JBC.M706181200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
Download full validation report