2V1O

Crystal structure of N-terminal domain of acyl-CoA thioesterase 7

2V1O の概要

• エントリーDOI: 10.2210/pdb2v1o/pdb
• 分子名称: CYTOSOLIC ACYL COENZYME A THIOESTER HYDROLASE, COENZYME A (3 entities in total)
• 機能のキーワード: hydrolase, acyl-coa thioesterase 7, serine esterase, protein structure, domain duplication, acot7, macrophage, hotdog domain
• 由来する生物種: MUS MUSCULUS (MOUSE)
• 細胞内の位置: Isoform A: Cytoplasm. Isoform D: Cytoplasm: Q91V12
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 106187.99

構造登録者

Forwood, J.K.,Thakur, A.S.,Guncar, G.,Marfori, M.,Mouradov, D.,Meng, W.N.,Robinson, J.,Huber, T.,Kellie, S.,Martin, J.L.,Hume, D.A.,Kobe, B. (登録日: 2007-05-28, 公開日: 2007-06-26, 最終更新日: 2024-05-08)

• 主引用文献: Forwood, J.K.,Thakur, A.S.,Guncar, G.,Marfori, M.,Mouradov, D.,Meng, W.N.,Robinson, J.,Huber, T.,Kellie, S.,Martin, J.L.,Hume, D.A.,Kobe, B.; Structural Basis for Recruitment of Tandem Hotdog Domains in Acyl-Coa Thioesterase 7 and its Role in Inflammation.; Proc.Natl.Acad.Sci.USA, 104:10382-, 2007; PubMed: 17563367; DOI: 10.1073/PNAS.0700974104

実験手法

X-RAY DIFFRACTION (1.78 Å)