2V17

Structure of the complex of antibody MN423 with a fragment of tau protein

Summary for 2V17

• Entry DOI: 10.2210/pdb2v17/pdb
• Descriptor: PEPTIDE FRAGMENT, MONOCLONAL ANTIBODY FAB FRAGMENT MN423, ... (4 entities in total)
• Functional Keywords: microtubule, tau protein, alzheimer's disease, immune system
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 3
• Total formula weight: 47905.14

Authors

Sevcik, J.,Skrabana, R.,Csokova, N.,Dvorsky, R.,Novak, M. (deposition date: 2007-05-22, release date: 2007-12-25, Last modification date: 2023-12-13)

• Primary citation: Sevcik, J.,Skrabana, R.,Dvorsky, R.,Csokova, N.,Iqbal, K.,Novak, M.; X-Ray Structure of the Phf Core C-Terminus: Insight Into the Folding of the Intrinsically Disordered Protein Tau in Alzheimer'S Disease.; FEBS Lett., 581:5872-, 2007; PubMed: 18061582; DOI: 10.1016/J.FEBSLET.2007.11.067

Experimental method

X-RAY DIFFRACTION (1.65 Å)