2UZP

Crystal structure of the C2 domain of human protein kinase C gamma.

Summary for 2UZP

DescriptorPROTEIN KINASE C GAMMA TYPE, PYRIDOXAL-5'-PHOSPHATE, COBALT (II) ION, ... (7 entities in total)
Functional Keywordstransferase, metal-binding, kinase, zinc-finger, atp-binding, spinocerebellar ataxia, calcium-binding protein, serine/threonine-protein kinase, phospholipid binding protein, nucleotide-binding, phorbol- ester binding, phosphorylation, protein kinase c, neurodegeneration
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm  P05129
Total number of polymer chains3
Total molecular weight53297.69
Authors
Primary citation
Pike, A.C.W.,Amos, A.,Johansson, C.,Sobott, F.,Savitsky, P.,Berridge, G.,Fedorov, O.,Umeano, C.,Gorrec, F.,Bunkoczi, G.,Debreczeni, J.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Weigelt, J.,Sundstrom, M.,Knapp, S.
Crystal Structure of C2 Domain of Protein Kinase C Gamma
To be Published,
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliers0.20841.0%0.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution