2UYJ

Crystal structure of E. coli TdcF with bound ethylene glycol

2UYJ の概要

• エントリーDOI: 10.2210/pdb2uyj/pdb
• 関連するPDBエントリー: 2UYK 2UYN 2UYP
• 分子名称: PROTEIN TDCF, 1,2-ETHANEDIOL (3 entities in total)
• 機能のキーワード: yjgf/yer057c/uk114 family, ethylene glycol, unknown function, tdcf protein, ligand binding, 2-ketobutyrate
• 由来する生物種: ESCHERICHIA COLI
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 42328.45

構造登録者

Burman, J.D.,Stevenson, C.E.M.,Sawers, R.G.,Lawson, D.M. (登録日: 2007-04-10, 公開日: 2007-05-29, 最終更新日: 2023-12-13)

主引用文献

Burman, J.D.,Stevenson, C.E.M.,Sawers, R.G.,Lawson, D.M.
The Crystal Structure of Escherichia Coli Tdcf, a Member of the Highly Conserved Yjgf/Yer057C/Uk114 Family.
Bmc Struct.Biol., 7:30-, 2007

PubMed Abstract: The YjgF/YER057c/UK114 family of proteins is widespread in nature, but has as yet no clearly defined biological role. Members of the family exist as homotrimers and are characterised by intersubunit clefts that are delineated by well-conserved residues; these sites are likely to be of functional significance, yet catalytic activity has never been detected for any member of this family. The gene encoding the TdcF protein of E. coli, a YjgF/YER057c/UK114 family member, resides in an operon that strongly suggests a role in the metabolism of 2-ketobutyrate for this protein.

PubMed: 17506874
DOI: 10.1186/1472-6807-7-30

実験手法

X-RAY DIFFRACTION (2.35 Å)