2UXT
SufI Protein from Escherichia Coli
Summary for 2UXT
| Entry DOI | 10.2210/pdb2uxt/pdb |
| Related | 2UXV |
| Descriptor | PROTEIN SUFI (2 entities in total) |
| Functional Keywords | oxidoreductase, sufi, periplasmic, cupredoxin-like, fts mutant suppressor |
| Biological source | ESCHERICHIA COLI |
| Total number of polymer chains | 2 |
| Total formula weight | 100489.52 |
| Authors | Tarry, M.J.,Roversi, P.,Sargent, F.,Berks, B.C.,Lea, S.M. (deposition date: 2007-03-29, release date: 2008-05-13, Last modification date: 2023-12-13) |
| Primary citation | Tarry, M.,Arends, S.J.,Roversi, P.,Piette, E.,Sargent, F.,Berks, B.C.,Weiss, D.S.,Lea, S.M. The Escherichia Coli Cell Division Protein and Model Tat Substrate Sufi (Ftsp) Localizes to the Septal Ring and Has a Multicopper Oxidase-Like Structure. J.Mol.Biol., 386:504-, 2009 Cited by PubMed Abstract: The Escherichia coli protein SufI (FtsP) has recently been proposed to be a component of the cell division apparatus. The SufI protein is also in widespread experimental use as a model substrate in studies of the Tat (twin arginine translocation) protein transport system. We have used SufI-GFP (green fluorescent protein) fusions to show that SufI localizes to the septal ring in the dividing cell. We have also determined the structure of SufI by X-ray crystallography to a resolution of 1.9 A. SufI is structurally related to the multicopper oxidase superfamily but lacks metal cofactors. The structure of SufI suggests it serves a scaffolding rather than an enzymatic role in the septal ring and reveals regions of the protein likely to be involved in the protein-protein interactions required to assemble SufI at the septal ring. PubMed: 19135451DOI: 10.1016/J.JMB.2008.12.043 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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