2UXT

SufI Protein from Escherichia Coli

2UXT の概要

• エントリーDOI: 10.2210/pdb2uxt/pdb
• 関連するPDBエントリー: 2UXV
• 分子名称: PROTEIN SUFI (2 entities in total)
• 機能のキーワード: oxidoreductase, sufi, periplasmic, cupredoxin-like, fts mutant suppressor
• 由来する生物種: ESCHERICHIA COLI
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 100489.52

構造登録者

Tarry, M.J.,Roversi, P.,Sargent, F.,Berks, B.C.,Lea, S.M. (登録日: 2007-03-29, 公開日: 2008-05-13, 最終更新日: 2023-12-13)

主引用文献

Tarry, M.,Arends, S.J.,Roversi, P.,Piette, E.,Sargent, F.,Berks, B.C.,Weiss, D.S.,Lea, S.M.
The Escherichia Coli Cell Division Protein and Model Tat Substrate Sufi (Ftsp) Localizes to the Septal Ring and Has a Multicopper Oxidase-Like Structure.
J.Mol.Biol., 386:504-, 2009

PubMed Abstract: The Escherichia coli protein SufI (FtsP) has recently been proposed to be a component of the cell division apparatus. The SufI protein is also in widespread experimental use as a model substrate in studies of the Tat (twin arginine translocation) protein transport system. We have used SufI-GFP (green fluorescent protein) fusions to show that SufI localizes to the septal ring in the dividing cell. We have also determined the structure of SufI by X-ray crystallography to a resolution of 1.9 A. SufI is structurally related to the multicopper oxidase superfamily but lacks metal cofactors. The structure of SufI suggests it serves a scaffolding rather than an enzymatic role in the septal ring and reveals regions of the protein likely to be involved in the protein-protein interactions required to assemble SufI at the septal ring.

PubMed: 19135451
DOI: 10.1016/J.JMB.2008.12.043

実験手法

X-RAY DIFFRACTION (1.9 Å)