2UV0

Structure of the P. aeruginosa LasR ligand-binding domain bound to its autoinducer

2UV0 の概要

• エントリーDOI: 10.2210/pdb2uv0/pdb
• 分子名称: TRANSCRIPTIONAL ACTIVATOR PROTEIN LASR, N-3-OXO-DODECANOYL-L-HOMOSERINE LACTONE (3 entities in total)
• 機能のキーワード: transcription, acyl-homoserine lactone receptor, quorum sensing, transcription regulation, alpha-beta-alpha sandwich
• 由来する生物種: PSEUDOMONAS AERUGINOSA
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 79935.42

構造登録者

Bottomley, M.J.,Muraglia, E.,Bazzo, R.,Carfi, A. (登録日: 2007-03-08, 公開日: 2007-03-27, 最終更新日: 2019-07-24)

• 主引用文献: Bottomley, M.J.,Muraglia, E.,Bazzo, R.,Carfi, A.; Molecular Insights Into Quorum Sensing in the Human Pathogen Pseudomonas Aeruginosa from the Structure of the Virulence Regulator Lasr Bound to its Autoinducer.; J.Biol.Chem., 282:13592-, 2007; PubMed: 17363368; DOI: 10.1074/JBC.M700556200

実験手法

X-RAY DIFFRACTION (1.8 Å)