2TRH
TERTIARY STRUCTURES OF THREE AMYLOIDOGENIC TRANSTHYRETIN VARIANTS AND IMPLICATIONS FOR AMYLOID FIBRIL FORMATION
Summary for 2TRH
Entry DOI | 10.2210/pdb2trh/pdb |
Descriptor | TRANSTHYRETIN (2 entities in total) |
Functional Keywords | albumin, transport, retinol-binding, vitamin a, amyloid, thyroid hormone, liver, plasma, cerebrospinal fluid, polyneuropathy, disease mutation, thyroxine, prealbumin |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P02766 |
Total number of polymer chains | 2 |
Total formula weight | 27662.82 |
Authors | Schormann, N.,Murrell, J.R.,Benson, M.D. (deposition date: 1996-10-16, release date: 1997-04-21, Last modification date: 2024-05-22) |
Primary citation | Schormann, N.,Murrell, J.R.,Benson, M.D. Tertiary structures of amyloidogenic and non-amyloidogenic transthyretin variants: new model for amyloid fibril formation. Amyloid, 5:175-187, 1998 Cited by PubMed: 9818054PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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